Re: [cml 2] Need some help -- Drug Interactions In Imatinib Therapy
yusef,
I have had the same problem. Don't worry abou the antibiotic. It just
enhances the Fleevec, makes it stronger. You wil only be one it for about 10
days. You really need the treatment, as it can get worse and become more
painful.
Shelley
Yusuf Cipe <cipeyusuf@...
Hello all,
For a while i'm having some trouble with my stomach. Endoscopy results shows
that there is bacterium called helicobacter pylori in my stomach which causes
serious stomach problems. So my doctor told me to begin an antibiotics therapy
for a week which contains 1000 mg clarithromycin every day. I asked him if there
is an interaction between gleevec and this antibiotics and his answer was "no".
The problem is that i searched the web and read that there is an interaction
between imatinib and clarithromycin. I'm really confused now and i dont know
what to do. I will be very happy if someone has a knowledge or idea about this.
http://medicineworld.org/cancer/lead/2-2006/drug-interactions-in-imatinib-therap\
y.html
http://www.drugs.com/mtm/gleevec.html
Thank you very much.
Yusuf Cipe
Istanbul
Hello Yusef,
My sister has CML (400 ml daily) and is recovering from colon cancer surgery
(Sept. 2006). When I read your post, I felt like she had written it. One month
ago, she also was diagnosed with the bacteria H -Pylori and given that
same medication. Two weeks later, she became very ill. She had flu like
symptoms at first and then suddenly lost all control of bowels movements. She
has
to be hospitalized and was diagnosed with a very serious disease called C.
diff (google that). She was on IV's for a long time. This is such a hard
contagious medical adverse reaction for the body to handle. Hospitals do not
like to have patients sick with c-diff..it travels fast. She is recovering
slowly, but anyone who has ever heard of this disease knows that this takes a
long time and it is very serious.
We know that everyone reacts differently to medications based on their
own health at the time. We don't know if this was a drug interaction with
Gleevec or what, but, we urge you to do just what the Internet recommendation
says:
Monitor for adverse events.
Sincerely,
Jan
janw815@...
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Hi Jan,
I'm sorry to hear about your sister's struggles and I hope she
recovers very soon.
C Difficile is a bacteria that you acquire, usually after you've been
on antibiotics for a while and usually when a patient has been in a
hospital where the bacteria is present. It's not something that you
get from a drug interaction between Gleevec and an antibiotic, it's a
bacteria that you catch.
I wish you and your sister the best,
Tracey